Life Sciences

aid: life-sciences
url: >-
  https://raw.githubusercontent.com/api-evangelist/life-sciences/refs/heads/main/apis.yml
name: Life Sciences
type: Index
image: https://kinlane-productions.s3.amazonaws.com/apis-json/apis-json-logo.jpg
tags:
  - Life Sciences
  - Biotech
  - Pharma
  - Healthcare
  - Clinical Trials
  - Drug Information
  - Genomics
  - Bioinformatics
  - EHR
  - FHIR
  - Lab Informatics
description: >-
  Industry-vertical index for the life sciences, biotechnology, and
  pharmaceutical landscape. Catalogs the major public and commercial APIs
  spanning clinical trial registries, drug and regulatory data, genomic
  reference data, electronic health record exchange, laboratory informatics
  systems, and bioinformatics pipeline platforms. The catalog is anchored by
  shared schemas for the three core records that recur across this domain:
  the clinical trial, the drug, and the gene.
created: '2025-01-01'
modified: '2026-05-23'
specificationVersion: '0.19'
apis:
  - name: ClinicalTrials.gov API v2
    description: >-
      The U.S. National Library of Medicine's modernized REST/JSON API for the
      ClinicalTrials.gov registry. Provides programmatic access to records of
      privately and publicly funded clinical studies conducted around the
      world, replacing the legacy AACT/full-study download path with a
      JSON-first interface and OpenAPI specification.
    humanURL: https://clinicaltrials.gov/data-api/api
    baseURL: https://clinicaltrials.gov/api/v2/
    tags:
      - Clinical Trials
      - Registry
      - NIH
      - NLM
      - Public Data
    properties:
      - type: Documentation
        url: https://clinicaltrials.gov/data-api/api
      - type: Documentation
        url: https://clinicaltrials.gov/data-api/about-api
        title: About the API
      - type: OpenAPI
        url: https://clinicaltrials.gov/api/v2/swagger.yaml
        title: ClinicalTrials.gov v2 OpenAPI
      - type: JSONSchema
        url: >-
          https://raw.githubusercontent.com/api-evangelist/life-sciences/refs/heads/main/json-schema/clinical-trial-schema.json
        title: Clinical Trial Schema
      - type: Example
        url: >-
          https://raw.githubusercontent.com/api-evangelist/life-sciences/refs/heads/main/examples/clinical-trial-example.json
        title: Clinical Trial Example
  - name: EU Clinical Trials Register / CTIS
    description: >-
      The European Medicines Agency's Clinical Trials Information System
      (CTIS) and the legacy EU Clinical Trials Register. CTIS is the single
      entry point for sponsors and regulators across the EU/EEA to submit and
      supervise clinical trials under Regulation (EU) No 536/2014. Public
      lookup is offered through a web portal; bulk and integration interfaces
      are not openly published as REST APIs.
    humanURL: https://euclinicaltrials.eu/
    baseURL: https://euclinicaltrials.eu/ctis-public/
    tags:
      - Clinical Trials
      - EU
      - EMA
      - Regulator
      - CTIS
    properties:
      - type: Documentation
        url: https://euclinicaltrials.eu/
      - type: Documentation
        url: https://www.ema.europa.eu/en/human-regulatory-overview/research-development/clinical-trials-human-medicines/clinical-trials-information-system
        title: EMA CTIS overview
      - type: HumanInterface
        url: https://www.clinicaltrialsregister.eu/
        title: Legacy EU Clinical Trials Register
  - name: openFDA
    description: >-
      A U.S. Food and Drug Administration project that exposes public FDA data
      via a single Elasticsearch-backed REST/JSON API. Covers adverse-event
      reports, drug labels, recalls, NDC directory, device 510(k) and adverse
      events, food enforcement, tobacco problem reports, and animal/vet
      adverse events.
    humanURL: https://open.fda.gov/
    baseURL: https://api.fda.gov/
    tags:
      - FDA
      - Drug
      - Device
      - Food
      - Adverse Events
      - Regulator
    properties:
      - type: Documentation
        url: https://open.fda.gov/apis/
      - type: Documentation
        url: https://open.fda.gov/apis/drug/
        title: Drug endpoints
      - type: Documentation
        url: https://open.fda.gov/apis/device/
        title: Device endpoints
      - type: Documentation
        url: https://open.fda.gov/apis/food/
        title: Food endpoints
      - type: GitHubRepository
        url: https://github.com/FDA/openfda
      - type: JSONSchema
        url: >-
          https://raw.githubusercontent.com/api-evangelist/life-sciences/refs/heads/main/json-schema/drug-schema.json
        title: Drug Schema
      - type: Example
        url: >-
          https://raw.githubusercontent.com/api-evangelist/life-sciences/refs/heads/main/examples/drug-example.json
        title: Drug Example
  - name: DailyMed
    description: >-
      The National Library of Medicine's authoritative source of FDA-approved
      Structured Product Labeling (SPL) for prescription and over-the-counter
      medications marketed in the United States. Exposes a REST/JSON web
      services API for searching and retrieving SPL documents by SET ID, NDC,
      RxCUI, and other identifiers.
    humanURL: https://dailymed.nlm.nih.gov/dailymed/
    baseURL: https://dailymed.nlm.nih.gov/dailymed/services/v2/
    tags:
      - Drug Information
      - Labeling
      - SPL
      - NLM
    properties:
      - type: Documentation
        url: https://dailymed.nlm.nih.gov/dailymed/app-support-web-services.cfm
        title: DailyMed Web Services
  - name: RxNorm API
    description: >-
      The National Library of Medicine's web service for accessing RxNorm, the
      standardized nomenclature for clinical drugs that links names of drugs
      across the major U.S. drug vocabularies. Supports name-to-RxCUI
      resolution, NDC lookup, relationship traversal, interaction discovery
      via RxNav, and approximate matching.
    humanURL: https://lhncbc.nlm.nih.gov/RxNav/APIs/RxNormAPIs.html
    baseURL: https://rxnav.nlm.nih.gov/REST/
    tags:
      - Drug Information
      - Terminology
      - NLM
      - RxNorm
    properties:
      - type: Documentation
        url: https://lhncbc.nlm.nih.gov/RxNav/APIs/RxNormAPIs.html
      - type: Documentation
        url: https://lhncbc.nlm.nih.gov/RxNav/APIs/InteractionAPIs.html
        title: Interaction API
      - type: JSONSchema
        url: >-
          https://raw.githubusercontent.com/api-evangelist/life-sciences/refs/heads/main/json-schema/drug-schema.json
        title: Drug Schema
  - name: DrugBank API
    description: >-
      A commercial drug knowledge API providing curated pharmacology,
      pharmacokinetics, drug-drug interaction, indication, and identifier
      cross-walk data covering small molecules and biologics. Used by clinical
      decision support, electronic prescribing, and pharmacy systems.
    humanURL: https://docs.drugbank.com/v1/
    baseURL: https://api.drugbankplus.com/v1/
    tags:
      - Drug Information
      - Pharmacology
      - Interactions
      - Commercial
    properties:
      - type: Documentation
        url: https://docs.drugbank.com/v1/
      - type: Documentation
        url: https://go.drugbank.com/
        title: DrugBank Online
  - name: NCBI Entrez E-utilities
    description: >-
      The set of nine programmatic interfaces (ESearch, EPost, ESummary,
      EFetch, ELink, EInfo, EGQuery, ESpell, ECitMatch) that provide unified
      access to all NCBI databases including PubMed, Gene, Genome, Nucleotide,
      Protein, ClinVar, dbSNP, dbGaP, BioProject, BioSample, GEO, and Taxonomy.
    humanURL: https://www.ncbi.nlm.nih.gov/books/NBK25500/
    baseURL: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/
    tags:
      - Genomics
      - Bioinformatics
      - NCBI
      - PubMed
      - Reference Data
    properties:
      - type: Documentation
        url: https://www.ncbi.nlm.nih.gov/books/NBK25500/
      - type: Documentation
        url: https://www.ncbi.nlm.nih.gov/books/NBK25501/
        title: A General Introduction to the E-utilities
      - type: JSONSchema
        url: >-
          https://raw.githubusercontent.com/api-evangelist/life-sciences/refs/heads/main/json-schema/gene-schema.json
        title: Gene Schema
  - name: Ensembl REST API
    description: >-
      The European Bioinformatics Institute's REST/JSON interface to the
      Ensembl genome browser. Provides programmatic access to genomic
      annotation, variation, comparative genomics, regulatory data, the
      Variant Effect Predictor (VEP), and GA4GH-compatible variation
      endpoints across vertebrate, invertebrate, plant, and fungal genomes.
    humanURL: https://rest.ensembl.org/
    baseURL: https://rest.ensembl.org/
    tags:
      - Genomics
      - Variation
      - VEP
      - EBI
      - GA4GH
    properties:
      - type: Documentation
        url: https://rest.ensembl.org/
      - type: Documentation
        url: https://rest.ensembl.org/documentation/info/vep_hgvs_get
        title: VEP endpoints
      - type: JSONSchema
        url: >-
          https://raw.githubusercontent.com/api-evangelist/life-sciences/refs/heads/main/json-schema/gene-schema.json
        title: Gene Schema
      - type: Example
        url: >-
          https://raw.githubusercontent.com/api-evangelist/life-sciences/refs/heads/main/examples/gene-example.json
        title: Gene Example
  - name: UCSC Genome Browser REST API
    description: >-
      The University of California Santa Cruz Genome Browser's REST API for
      programmatic retrieval of assemblies, tracks, sequences, and annotations
      across the genomes hosted in the UCSC Browser, including human (hg19,
      hg38, T2T-CHM13), mouse, and many other species.
    humanURL: https://genome.ucsc.edu/goldenPath/help/api.html
    baseURL: https://api.genome.ucsc.edu/
    tags:
      - Genomics
      - Reference Genome
      - UCSC
      - Tracks
    properties:
      - type: Documentation
        url: https://genome.ucsc.edu/goldenPath/help/api.html
  - name: ClinVar (via E-utilities)
    description: >-
      The NIH/NLM database of relationships among human genomic variation and
      phenotype, with supporting evidence. Accessible programmatically via
      Entrez E-utilities and via a structured FTP feed of XML/JSON variant
      submissions.
    humanURL: https://www.ncbi.nlm.nih.gov/clinvar/
    baseURL: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/
    tags:
      - Variation
      - Clinical Genomics
      - NCBI
      - ClinVar
    properties:
      - type: Documentation
        url: https://www.ncbi.nlm.nih.gov/clinvar/docs/maintenance_use/
      - type: Documentation
        url: https://www.ncbi.nlm.nih.gov/clinvar/docs/linking/
        title: Linking to ClinVar
  - name: dbSNP (via E-utilities)
    description: >-
      The NCBI Short Genetic Variations database, the canonical reference for
      single nucleotide polymorphisms (SNPs) and small insertions/deletions in
      humans and other organisms. Accessed via Entrez E-utilities using the
      `snp` database.
    humanURL: https://www.ncbi.nlm.nih.gov/snp/
    baseURL: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/
    tags:
      - Variation
      - SNP
      - NCBI
      - dbSNP
    properties:
      - type: Documentation
        url: https://www.ncbi.nlm.nih.gov/snp/docs/
  - name: HL7 FHIR
    description: >-
      Fast Healthcare Interoperability Resources (FHIR) is HL7's standard for
      health care data exchange. The current normative version is R5, released
      March 2023. Defines roughly 150 resource types covering administration,
      clinical care, diagnostics, medications, workflow, financial, and
      foundation domains, exchanged over REST, messaging, or document
      paradigms.
    humanURL: https://www.hl7.org/fhir/
    baseURL: https://hl7.org/fhir/R5/
    tags:
      - FHIR
      - HL7
      - EHR
      - Healthcare Interoperability
      - Standard
    properties:
      - type: Documentation
        url: https://www.hl7.org/fhir/
      - type: Specification
        url: https://hl7.org/fhir/R5/
        title: FHIR R5 specification
      - type: JSONSchema
        url: https://hl7.org/fhir/R5/fhir.schema.json.zip
        title: FHIR JSON Schema (official)
      - type: GitHubRepository
        url: https://github.com/HL7/fhir
  - name: SMART on FHIR
    description: >-
      An open-spec authorization profile layered on top of FHIR that enables
      third-party clinical applications to launch within an EHR session with
      OAuth 2.0 / OpenID Connect scopes scoped to FHIR resources.
    humanURL: https://docs.smarthealthit.org/
    baseURL: https://docs.smarthealthit.org/
    tags:
      - FHIR
      - SMART
      - OAuth
      - EHR
      - Standard
    properties:
      - type: Documentation
        url: https://docs.smarthealthit.org/
      - type: GitHubRepository
        url: https://github.com/smart-on-fhir
  - name: Benchling Developer Platform
    description: >-
      Benchling's REST API and webhook platform for its R&D cloud, exposing
      programmatic access to the Notebook (entries), Registry (registered
      entities, sequences, plasmids), Inventory (boxes, plates, locations),
      Requests, Results, Schemas, and Projects domains used across biotech
      R&D organizations.
    humanURL: https://docs.benchling.com/
    baseURL: https://{tenant}.benchling.com/api/v2/
    tags:
      - Lab Informatics
      - ELN
      - LIMS
      - Biotech
      - Commercial
    properties:
      - type: Documentation
        url: https://docs.benchling.com/
      - type: Documentation
        url: https://docs.benchling.com/reference
        title: API reference
  - name: TetraScience Data Platform
    description: >-
      A cloud-native scientific data platform that harmonizes instrument and
      informatics data across pharma R&D. Exposes REST APIs and SDKs for
      ingesting, querying, and integrating laboratory and computational data
      using the Intermediate Data Schema (IDS).
    humanURL: https://developers.tetrascience.com/
    baseURL: https://developers.tetrascience.com/
    tags:
      - Lab Informatics
      - Scientific Data
      - IDS
      - Commercial
    properties:
      - type: Documentation
        url: https://developers.tetrascience.com/
  - name: Sapio Sciences ELN/LIMS API
    description: >-
      Sapio Sciences' platform API providing programmatic access to its
      Electronic Laboratory Notebook, Laboratory Information Management
      System, and Scientific Data Cloud, covering samples, experiments,
      assay results, and inventory.
    humanURL: https://www.sapiosciences.com/
    baseURL: https://www.sapiosciences.com/
    tags:
      - Lab Informatics
      - ELN
      - LIMS
      - Commercial
    properties:
      - type: Documentation
        url: https://www.sapiosciences.com/
  - name: DNAnexus Platform API
    description: >-
      DNAnexus is a cloud bioinformatics platform used by pharma, biotech, and
      research institutions to run genomic and biomedical compute workflows.
      Its platform API provides programmatic access to projects, files, apps,
      workflows, jobs, and analyses for petabyte-scale genomic data.
    humanURL: https://documentation.dnanexus.com/
    baseURL: https://api.dnanexus.com/
    tags:
      - Bioinformatics
      - Cloud Compute
      - Workflows
      - Commercial
    properties:
      - type: Documentation
        url: https://documentation.dnanexus.com/
      - type: Documentation
        url: https://documentation.dnanexus.com/developer/api
        title: Developer / API reference
  - name: Seven Bridges (Velsera) Platform API
    description: >-
      A multi-cloud bioinformatics platform (now part of Velsera) offering
      hosted instances of the NCI Cancer Genomics Cloud and other cohort
      analysis environments. Provides REST APIs for projects, files, tasks,
      and apps written in CWL.
    humanURL: https://docs.sevenbridges.com/
    baseURL: https://api.sbgenomics.com/v2/
    tags:
      - Bioinformatics
      - Cloud Compute
      - CWL
      - Cancer Genomics
    properties:
      - type: Documentation
        url: https://docs.sevenbridges.com/
  - name: Galaxy Project API
    description: >-
      The open-source Galaxy bioinformatics workbench exposes a REST API for
      managing histories, datasets, workflows, tools, jobs, and users across
      community Galaxy servers and self-hosted installations.
    humanURL: https://docs.galaxyproject.org/en/latest/api_doc.html
    baseURL: https://usegalaxy.org/api/
    tags:
      - Bioinformatics
      - Open Source
      - Workflows
      - Galaxy
    properties:
      - type: Documentation
        url: https://docs.galaxyproject.org/en/latest/api_doc.html
      - type: GitHubRepository
        url: https://github.com/galaxyproject/galaxy
  - name: GA4GH APIs (htsget, DRS, WES, TES, Beacon)
    description: >-
      The Global Alliance for Genomics and Health publishes a suite of open
      REST specifications enabling federated access to genomic data and
      compute. Includes htsget (sequencing reads), DRS (Data Repository
      Service), WES (Workflow Execution Service), TES (Task Execution
      Service), and the Beacon variant-discovery protocol.
    humanURL: https://www.ga4gh.org/genomic-data-toolkit/
    baseURL: https://www.ga4gh.org/
    tags:
      - Genomics
      - Standard
      - GA4GH
      - Federated
    properties:
      - type: Documentation
        url: https://www.ga4gh.org/genomic-data-toolkit/
      - type: GitHubRepository
        url: https://github.com/ga4gh
      - type: Specification
        url: https://samtools.github.io/hts-specs/htsget.html
        title: htsget specification
      - type: Specification
        url: https://ga4gh.github.io/beacon/
        title: Beacon specification
json-schemas:
  - title: Clinical Trial
    url: >-
      https://raw.githubusercontent.com/api-evangelist/life-sciences/refs/heads/main/json-schema/clinical-trial-schema.json
  - title: Drug
    url: >-
      https://raw.githubusercontent.com/api-evangelist/life-sciences/refs/heads/main/json-schema/drug-schema.json
  - title: Gene
    url: >-
      https://raw.githubusercontent.com/api-evangelist/life-sciences/refs/heads/main/json-schema/gene-schema.json
json-ld:
  - title: Life Sciences Context
    url: >-
      https://raw.githubusercontent.com/api-evangelist/life-sciences/refs/heads/main/json-ld/life-sciences-context.jsonld
vocabulary:
  - title: Life Sciences Vocabulary
    url: >-
      https://raw.githubusercontent.com/api-evangelist/life-sciences/refs/heads/main/vocabulary/life-sciences-vocabulary.yaml
maintainers:
  - FN: Kin Lane
    email: [email protected]
    url: https://apievangelist.com